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I wrote this song in This version was recorded early with the band Phono.

Your current browser isn't compatible with SoundCloud. Please download one of our supported browsers. Need help? Chrome Firefox Safari Internet Explorer. Something went wrong Is your network connection unstable or browser outdated? I need help. Blood Adv ; 2 21 : — This approach should enable design of diagnostic and therapeutic reagents to treat platelet-specific alloimmune disorders.

Local residues surrounding polymorphic residue 33 are suspected to have a profound effect on alloantibody binding and subsequent downstream effector events.

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To define the molecular requirements for HPA-1a alloantibody binding, we generated transgenic mice that expressed murine GPIIIa muGPIIIa isoforms mna select humanized residues within the plexin-semaphorin-integrin PSI and epidermal growth factor 1 EGF1 domains and examined their ability to support the binding of a series of monoclonal and polyclonal HPA-1a—specific antibodies. These results reveal the previously unsuspected complex heterogeneity of the polyclonal alloimmune response to this clinically important human platelet alloantigen.

High-resolution mapping of this alloimmune response may improve diagnosis of FNAIT and should facilitate the rational design and Hot Frechen sluts of contemplated prophylactic and therapeutic anti—HPA-1a reagents.

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This Site. Google Scholar. Hartmut Weiler Hartmut Weiler. Brian R. Curtis Brian R. Jieqing Zhu Jieqing Zhu. Peter J. Newman Peter J. Blood Adv 2 21 : Article history Submitted:. ❶But the case has prompted outrage Ahle animal rights activists and others in the city of Ahlen, raised questions about the cruelty of the seizure and spurred debate about whether any German laws had been broken.

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Explore the largest community of artists, bands, podcasters and creators of music & audio. But the case has prompted outrage from animal rights activists and others in the city of Ahlen, raised questions about the cruelty of the seizure.